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Regenerative Engineering for Knee Osteoarthritis Treatment: Biomaterials and Cell-Based Technologies

Jorge L. Escobar Ivirico, Maumita Bhattacharjee, Emmanuel Kuyinu, Lakshmi S. Nair, Cato T. Laurencin

Engineering 2017, Volume 3, Issue 1,   Pages 16-27 doi: 10.1016/J.ENG.2017.01.003

Abstract:

Knee osteoarthritis (OA) is the most common form of arthritis worldwide.Two early targets of knee OA treatment include the predominant symptom of pain, and cartilage damagein the knee joint.Current treatments have been beneficial in treating the disease but none is as effective as total kneeIn this review, we discuss the pathogenesis of pain and cartilage damage in knee OA and explore novel

Keywords： Knee osteoarthritis     Osteoarthritic pain     Mesenchymal stem cells     Biomaterials     Regenerative engineering    

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Biomechanics of knee joint – A review

Bhaskar Kumar MADETI,Srinivasa Rao CHALAMALASETTI,S K Sundara siva rao BOLLA PRAGADA

Frontiers of Mechanical Engineering 2015, Volume 10, Issue 2,   Pages 176-186 doi: 10.1007/s11465-014-0306-x

Abstract:

The present paper is to know how the work is carried out in the field of biomechanics of knee.Knee geometry is a crucial part of human body movement, in which how various views of knee is shown inIt leads to know the forces acting on the knee joint.Experimental studies of knee geometry and forces acting on knee shown by various researchers have beenIn addition, static and dynamic analysis of knee has been also discussed respectively to some extent.

Keywords： biomechanics     knee geometry     ligaments     squat     femorotibial joint     finite element method    

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Experimental study on slender buckling-restrained knee braces with round steel bar cores

Frontiers of Structural and Civil Engineering 2023, Volume 17, Issue 1,   Pages 99-121 doi: 10.1007/s11709-022-0875-4

Abstract: This study aimed to investigate a novel slender buckling-restrained knee brace damper (BRKB) for welded

Keywords： beam-to-column connections     moment-resisting frame     cyclic and compression loading tests     buckling-restrained knee    

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Performance assessment of innovative seismic resilient steel knee braced frame

Tony T. Y. YANG,Yuanjie LI

Frontiers of Structural and Civil Engineering 2016, Volume 10, Issue 3,   Pages 291-302 doi: 10.1007/s11709-016-0340-3

Abstract: Buckling restrained knee braced truss moment frame (BRKBTMF) is a novel and innovative steel structural

Keywords： buckling restrained brace     innovative structural system     collapse simulation     seismic assessment    

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Impact of diabetes and its treatments on skeletal diseases

Wenbo Yan, Xin Li

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 81-90 doi: 10.1007/s11684-013-0243-9

Abstract: Risk for osteoarthritis is also elevated in diabetic population.Hyperglycemia and glucose derived AGEs could contribute to the development of osteoarthritis.

Keywords： diabetes     bone     osteoporosis     osteoarthritis    

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Unpowered Knee Exoskeleton Reduces Quadriceps Activity during Cycling Article

Ronnapee Chaichaowarat,Jun Kinugawa,Kazuhiro Kosuge

Engineering 2018, Volume 4, Issue 4,   Pages 471-478 doi: 10.1016/j.eng.2018.07.011

Abstract: cycling without providing an additional energy source, we have proposed the use of a torsion spring for knee-extensionWe developed an exoskeleton prototype using a crossing four-bar mechanism as a knee joint with an embeddedThis study evaluates the passive knee exoskeleton using constant-power cycling tests performed by eight

Keywords： Augmentation     Cycling     Energy cost     Electromyography     Exoskeleton     Knee     Orthosis     Muscle activity    

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Population-Based and Personalized Design of Total Knee Replacement Prosthesis for Additive Manufacturing Article

C.S. Chui, K.S. Leung, J. Qin, D. Shi, P. Augat, R.M.Y. Wong, S.K.H. Chow, X.Y. Huang, C.Y. Chen, Y.X. Lai, P.S.H. Yung, L. Qin, W.H. Cheung

Engineering 2021, Volume 7, Issue 3,   Pages 386-394 doi: 10.1016/j.eng.2020.02.017

Abstract:

At present, most total knee replacement (TKR) prostheses on the market are designed according to theA deformable three-dimensional (3D) knee model based on anatomical coordinates correlating with the identifiedand lowest amount of resected bone volume (27 412 mm3) in comparison with two commercial kneeThere is a need to develop an anthropometric-based knee prosthesis for the Chinese population.compared with current commercial prostheses, which is an essential step toward AM for personalized knee

Keywords： Additive manufacturing     Population-based design     Total knee replacement     Knee prosthesis     Anthropometric    

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Sensor-guided gait-synchronization lower-extremity-exoskeleton for potential application on unilateral knee-injured Research Articles

Donghai WANG

Frontiers of Information Technology & Electronic Engineering 2022, Volume 23, Issue 6,   Pages 920-936 doi: 10.1631/FITEE.2000465

Abstract:

This paper presents a gait-synchronization system to help potential unilateral knee-injured peopleThis relieves the body weight loading on the knee-injured leg and synchronizes its motion with that ofjoint-angle trajectories, the motorized hip joint lifts the links during walking and synchronizes the knee-injuredWe compare the measured joint-angle trajectories between the healthy and knee-injured legs, the simulatedknee forces, and the human-exoskeleton interaction forces.

Keywords： Sensor-guided     Lower-extremity-exoskeleton     Body sensor network     Gait synchronization     Weight-support    

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Multi-View Point-Based Registration for Native Knee Kinematics Measurement with Feature Transfer Learning Article

Cong Wang, Shuaining Xie, Kang Li, Chongyang Wang, Xudong Liu, Liang Zhao, Tsung-Yuan Tsai

Engineering 2021, Volume 7, Issue 6,   Pages 881-888 doi: 10.1016/j.eng.2020.03.016

Abstract: style="text-align: justify;">Deep-learning methods provide a promising approach for measuring in-vivo knee

Keywords： 2D–3D registration     Machine learning     Domain adaption     Point correspondence    

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Title Author Date Type Operation

Regenerative Engineering for Knee Osteoarthritis Treatment: Biomaterials and Cell-Based Technologies

Jorge L. Escobar Ivirico, Maumita Bhattacharjee, Emmanuel Kuyinu, Lakshmi S. Nair, Cato T. Laurencin

Journal Article

Biomechanics of knee joint – A review

Bhaskar Kumar MADETI,Srinivasa Rao CHALAMALASETTI,S K Sundara siva rao BOLLA PRAGADA

Journal Article

Experimental study on slender buckling-restrained knee braces with round steel bar cores

Journal Article

Performance assessment of innovative seismic resilient steel knee braced frame

Tony T. Y. YANG,Yuanjie LI

Journal Article

Impact of diabetes and its treatments on skeletal diseases

Wenbo Yan, Xin Li

Journal Article

Unpowered Knee Exoskeleton Reduces Quadriceps Activity during Cycling

Ronnapee Chaichaowarat,Jun Kinugawa,Kazuhiro Kosuge

Journal Article

Population-Based and Personalized Design of Total Knee Replacement Prosthesis for Additive Manufacturing

C.S. Chui, K.S. Leung, J. Qin, D. Shi, P. Augat, R.M.Y. Wong, S.K.H. Chow, X.Y. Huang, C.Y. Chen, Y.X. Lai, P.S.H. Yung, L. Qin, W.H. Cheung

Journal Article

Sensor-guided gait-synchronization lower-extremity-exoskeleton for potential application on unilateral knee-injured

Donghai WANG

Journal Article

Multi-View Point-Based Registration for Native Knee Kinematics Measurement with Feature Transfer Learning

Cong Wang, Shuaining Xie, Kang Li, Chongyang Wang, Xudong Liu, Liang Zhao, Tsung-Yuan Tsai

Journal Article